Yasaman Alaghband 1 , Janine L Kwapis 2 , Alberto J López 1 , André O White 1 , Osasumwen V Aimiuwu 1 , Amni Al-Kachak 1 , Kasuni K Bodinayake 1 , Nicole C Oparaugo 1 , Richard Dang 2 , Mariam Astarabadi 1 , Dina P Matheos 3 , Marcelo A Wood 4J Okombo, S Mok, T Qahash, T Yeo, J Bath, L Orchard, E Owens, Imhoi Koo, Istvan Albert, Manuel Llinás, D Fidock, 2022, PLoS Pathogens on p. e1010926 Addendum: Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoitesThe beneficial effect of prior experience on the acquisition of spatial memory in rats with CA1, but not large hippocampal lesions: a possible role for schema formationJ Okombo, S Mok, T Qahash, T Yeo, J Bath, L Orchard, E Owens, Imhoi Koo, Istvan Albert, Manuel Llinás, D Fidock, 2022, PLoS Pathogens on p. e1010926 Addendum: Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoitesPDF | On Mar 26, 2012, Marieke R Gilmartin and others published Trace and contextual fear conditioning are impaired following unilateral microinjection of muscimol in the ventral hippocampus or ...Janine L. Kwapis, Department of Biology, The Pennsylvania State University, 208 Mueller Laboratory, University Park, PA 16802, USA; e-mail: [email protected]. Metrics and citations MetricsJanine L. Kwapis. Janine L. Kwapis. Scilit Preprints.org Google Scholar * Department of Biology, Center for Molecular Investigation of Neurological Disorders (CMIND), Pennsylvania State University, University Park, PA 16802, USA * Author to whom correspondence should be addressed.Janine L. Kwapis; The circadian system influences many different biological processes, including memory performance. While the suprachiasmatic nucleus (SCN) functions as the brain's central ...Janine L. Kwapis: Conceptualization, Writing - original draft, Writing - review & editing, Supervision, Funding acquisition. Declaration of Competing Interest. The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.Alberto J. López, Yousheng Jia, André O. White, Janine L. Kwapis, Monica Espinoza, Philip Hwang, Rianne Campbell, Yasaman Alaghband, Om Chitnis, Dina P. Matheos ...Sep 1, 2015 · Recently, we demonstrated that the RSC is involved in trace fear extinction and retrieval (Kwapis, Jarome, Lee, Gilmartin, & Helmstetter, 2014), leading us to hypothesize that trace fear memory may be stored in a distributed cortical network that includes the prelimbic and retrosplenial cortices (Kwapis, Jarome, & Helmstetter, 2015). Finally, Bellfy and Kwapis review the evidence that the reconsolidation process may allow existing memories to update in response to new, relevant information . In their review, the authors outline the major behavioral paradigms used to study reconsolidation and describe the different molecular mechanisms across the brain that support this ...select article Elevated fear responses to threatening cues in rats with early life stress is associated with greater excitability and loss of gamma oscillations in ventral-medial prefrontal cortexJanine L. Kwapis, Ph.D., Department of Biology, Penn State University ... it is unknown whether these biological processes share a common mechanism that is altered with age. Dr. Kwapis will present evidence that epigenetic regulation of the circadian gene Period1 (Per1) in the dorsal hippocampus is critical for memory formation and contributes to age-related …Normal aging is accompanied by cognitive impairments, most notably disruptions in memory formation and updating, the ability to incorporate new information into existing memory. As lifespans increase...The retrosplenial cortex (RSC) is known to play a role in the retrieval of context memory, but its involvement in memory formation and consolidation is unclear. To better characterize the role of the RSC, we tested its involvement in the formation and ...All animals were handled for several days prior to surgery. Rats that underwent surgery were implanted with bilateral cannulas aimed at the amygdala [anteroposterior [AP], −2.8; Lateral [L], +/− 5.0; Ventral [V], −7.2]. Coordinates were chosen based on a rat brain atlas . Before surgery, each rat was anesthetized with an intraperitoneal ...ExampleOULTest Video: Video 1: ExampleOULTest.mpg. Title: Example Test session from OUL for scoring practice. This video is from an OUL test session with four young male C57BL/6J male mice run simultaneously. Two of these animals (the top right and bottom right boxes) were "No Update" animals and two animals each received a memory update (the mouse in the top left box had the right object ...This work was supported by NIMH and NIDA grants (MH81004, MH101491, DA025922, DA036984, DA031989) to M.A. Wood and NIA T32 grant AG000096-31 to J.L.K. Go to: GlossaryUndergraduate Research and Fellowships Mentoring Office. 321 Boucke Building. University Park, PA 16802. 814-863-8199 | [email protected]'s Disease affects 5.4 million Americans [1] and by 2030, approximately 13.8 million people 65 or older are projected to have the disease [2]. Even more individuals will experience normal age...Janine L. Kwapis and Marcelo A. Wood Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697, USA Post-traumatic stress disorder (PTSD) and other anxiety disorders stemming from dysregulated fear memory are problematic and costly. Understanding the molecular mechanismsThe best result we found for your search is Janine Lynn Kwapis age 30s in State College, PA in the Greentrees neighborhood. They have also lived in Shorewood, WI and Irvine, CA. Janine is related to Joseph Daniel Karbowski and Sonia B Kwapis as well as 3 additional people. Select this result to view Janine Lynn Kwapis's phone number, address, and more.Destiny S. Wright1, Kasuni K. Bodinayake1, Janine L. Kwapis1,* 1Department of Biology, Center for Molecular Investigation of Neurological Disorders (CMIND), Pennsylvania State University, University Park, PA, USA ... (Kwapis et al., 2019). This task is based on the object location memory (OLM) task (see Vogel-Ciernia & Wood, 2014) and therefore ...The Neuroscience section of the Current Protocols journal covers research methods involving molecular pathways, synaptic transmission, behavioral techniques & imaging.Jarome TJ, Kwapis JL, Werner CT, Parsons RG, Gafford GM, Helmstetter FJ (2012). The timing of multiple retrieval events can alter GluR1 phosphorylation and the requirement for protein synthesis in fear memory reconsolidation. Learn Mem 19: 300-306. [PMC free article] [Google Scholar] Jarome TJ, Werner CT, Kwapis JL, Helmstetter FJ (2011).Graham D. L. et al.. Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse. Nat. Neurosci. 10, 1029–1037 (2007). [Google Scholar] Graham D. L. et al.. Tropomyosin-related kinase B in the mesolimbic dopamine system: region-specific effects on cocaine reward. Biol. Psychiatry 65, 696–701 (2009).Our results demonstrate that impairments in Nr4a2 expression accompany cognitive deficits in aged mice and rats. Further, HDAC3 contributes to this age-related …Europe PMC is an archive of life sciences journal literature.Timothy J Jarome 1 , Janine L Kwapis , Wendy L Ruenzel , Fred J Helmstetter Affiliation 1 Department of Psychology, University of Wisconsin-Milwaukee …Janine L. Kwapis, PhD THE PAUL BERG EARLY CAREER PROFESSOR IN THE BIOLOGICAL SCIENCES; Assistant Professor of BiologyEpigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory. by Janine L Kwapis, Yasaman Alaghband, Enikö A Kramár, Alberto J López, Annie Vogel Ciernia, André O White, Guanhua Shu, Diane Rhee, Christina M Michael, Emilie Montellier, Yu Liu, Christophe N Magnan, Siwei Chen, Paolo Sassone …This work was supported by NIMH and NIDA grants (MH81004, MH101491, DA025922, DA036984, DA031989) to M.A. Wood and NIA T32 grant AG000096-31 to J.L.K. Go to: GlossaryBrandon L. Roberts; Ilia N. Karatsoreos; Research Open Access 06 Jun 2023 Scientific Reports. ... Janine L. Kwapis; Research 01 Jun 2023 Neuropsychopharmacology. P: 1-9. All Research & Reviews.Abstract. The circadian system plays an important role in aligning biological processes with the external time of day. A range of physiological functions are governed by the circadian …Janine L. Kwapis [email protected] Department of Biology, Center for Molecular Investigation of Neurological Disorders (CMIND), Pennsylvania State University, University Park, Pennsylvania. Corresponding author: [email protected] Search for more papers by this author. Destiny S. Wright, Destiny S. Wright.Neurobiology of learning and memory 128, 103-109. , 2016. 114. 2016. Trace and contextual fear conditioning are impaired following unilateral microinjection of muscimol in the ventral hippocampus or amygdala, but not the medial prefrontal cortex. MR Gilmartin, JL Kwapis, FJ Helmstetter. Neurobiology of learning and memory 97 (4), 452-464.Neurotree: academic genealogy for Janine Kwapis, Biology, The Pennsylvania State University-Eberly College of Science Adding trainee for Janine Kwapis Type a name and select match from the drop-down list. If no match exists, you will be prompted to add a newJanine L. Kwapis, Timothy J. Jarome and Fred J. Helmstetter; Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, USA; Corresponding author: fjh{at}uwm.edu; Abstract. The extinction of delay fear conditioning relies on a neural circuit that has received much attention and is relatively well defined. ...Janine L. Kwapis, Timothy J. Jarome and Fred J. Helmstetter; Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, USA; Corresponding author: fjh{at}uwm.edu; Abstract. The extinction of delay fear conditioning relies on a neural circuit that has received much attention and is relatively well defined. ...Consistent with this, exposure to new information is necessary for the reconsolidation process to be initiated; when retrieval contains only familiar information, the original memory remains stable (Diaz-Mataix, Ruiz Martinez, Schafe, LeDoux, & Doyere, 2013; Jarome, Ferrara, Kwapis, & Helmstetter, 2015; Kwapis et al., 2019; Kwapis, Jarome, Ferrara, & …If updating can reorganize the trace memory so that it relies on the delay circuit, after the memory restabilizes, the amygdala should be required for extinction (Kwapis et al, 2014a) and the RSC should no longer be involved in memory retrieval (Kwapis et al, 2014a; Kwapis et al, 2015b). Thus, we can test whether reconsolidation-dependent ...memory must be properly retrieved. Long-term memory is typically tested 24h or longer after acquisition, after the consolidation process is complete, and can be very long lasting,Assistant Professor of Biology Department of Biology jlk855 Janine Kwapis Biography Education B.A., Psychology, Alma College M.S., Behavioral Neuroscience, University of Wisconsin-Milwaukee Ph.D., Behavioral Neuroscience, University of Wisconsin-Milwaukee Postdoc Training University of California, Irvine Research InterestsJanine Kwapis, assistant professor of biology at Penn State, appointed as the Paul Berg Early Career Professor in the Biological Sciences About Eberly Leadership Meet the Dean Dean's Executive Team Sustainability Council Vision, Mission, and …AU - Kwapis, Janine L. N1 - Funding Information: This work was supported by the National Institutes of Health (grants R00AG056596 and R21AG068444) awarded to J.L.K.; the Whitehall Foundation (grant 2020-05-06 to J.L.K.); and was conducted while Janine Kwapis was a Glenn Foundation for Medical Research and AFAR Grant for Junior Faculty awardee ... The goal of our first experiment was to determine whether the maintenance of foreground context memory requires PKMζ activity in the BLA. To this end, we trained animals with context-only fear conditioning and infused ZIP or saline into the BLA 1 or 7 d later (Fig. 2 A). All animals showed normal acquisition of context-only fear conditioning before drug infusion (data not shown).Mark W. Urban, 1 Chenyu Lo, 1 Kasuni K. Bodinayake, 1 Chad A. Brunswick, 1 Shoko Murakami, 1 Ashley C. Heimann, 1 and Janine L. Kwapis 1 Mark W. Urban 1 Department of Biology, Pennsylvania State University, University Park, PA 16802, USA.CREST in the Nucleus Accumbens Core Regulates Cocaine Conditioned Place Preference, Cocaine-Seeking Behavior, and Synaptic PlasticityThe retrosplenial cortex is involved in the formation of memory for context and trace fear conditioning Janine L. Kwapis1, Timothy J. Jarome2, Jonathan L. Lee, Fred J. Helmstetter Department of Psychology, University of Wisconsin–Milwaukee, 2441 E. HartfordLauren Bellfy and Janine L. Kwapis * Department of Biology, Center for Molecular Investigation of Neurological Disorders (CMIND), Pennsylvania State University, University Park, PA 16802, USA; [email protected] * Correspondence: [email protected] Received: 22 August 2020; Accepted: 7 September 2020; Published: 9 September 2020AU - Kwapis, Janine L. N1 - Funding Information: This work was supported by the National Institutes of Health (grants R00AG056596 and R21AG068444) awarded to J.L.K.; the Whitehall Foundation (grant 2020-05-06 to J.L.K.); and was conducted while Janine Kwapis was a Glenn Foundation for Medical Research and AFAR Grant for Junior Faculty awardee ...International Journal of Molecular Sciences Editorial Special Issue “Molecular Mechanisms of Memory Formation and Modification” Timothy J. Jarome 1,2,* and Janine L. Kwapis 3,4,* Citation: Jarome, T.J.; Kwapis, J.L. Special Issue “Molecular MechanismsKv4 potassium channels modulate hippocampal EPSP-spike potentiation and spatial memory in rats . Bruno Truchet, ; Christine Manrique, ; Leam Sreng, ; Franck A. Chaillan,Dr. Diane Rhee, MD is a psychiatrist in New York, New York. Dr. Rhee is on Doximity. As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.Janine L. Kwapis [email protected] Department of Biology, Center for Molecular Investigation of Neurological Disorders (CMIND), Pennsylvania State University, University Park, Pennsylvania. Corresponding author: [email protected] Search for more papers by this author. Destiny S. Wright, Destiny S. Wright.Search life-sciences literature (42,985,652 articles, preprints and more) SearchFor delay conditioning, the UCS was delivered at the offset of the CS and the ITI was 110 ± 20 sec (total session duration, 17 min). Six-trial trace conditioning and four-trial delay conditioning produce similar levels of conditional fear to the CS (Kwapis et al. 2011). During training, rats learned to associate both the auditory CS and the ...27 Jan 2020 ... ... Janine L. Kwapis,. Corresponding Author. Janine L. Kwapis. [email protected]. Department of Biology, Center for Molecular Investigation of ...Europe PMC is an archive of life sciences journal literature.EV (Empty Vector) (Kwapis et al., 2017). For the DH experiments, 1 µlof virus was infused bilaterally. For the prelimbic and infralimbic experiments, 0.3 µl of virus was infused bilaterally. Immunofluorescence was used to confirm expression of HDAC3(Y298H). Injection needles were lowered to the desired coordinates at a rate of .2mm/15s. 2 ...We finally asked whether HDAC3 serine 424 phosphorylation (ser424) that controls HDAC3 activity and histone acetylation (Kwapis et al, 2017) is able to regulate DRG outgrowth. We overexpressed phospho‐mimetic or phospho‐dead HDAC3 S424A or S424D mutant plasmids in cultured DRG cells, respectively.ARTICLE Aging mice show impaired memory updating in the novel OUL updating paradigm Janine L. Kwapis1,2, Yasaman Alaghband 1, Ashley A. Keiser 1, Tri N. Dong , Christina M. Michael , Diane Rhee , Guanhua Shu , Richard T. Dang1, Dina P. Matheos1 and Marcelo A. Wood1 Memories do not persist in a permanent, static state but instead must be dynamically modified in response to new information.Sep 1, 2015 · Recently, we demonstrated that the RSC is involved in trace fear extinction and retrieval (Kwapis, Jarome, Lee, Gilmartin, & Helmstetter, 2014), leading us to hypothesize that trace fear memory may be stored in a distributed cortical network that includes the prelimbic and retrosplenial cortices (Kwapis, Jarome, & Helmstetter, 2015). Janine L. Kwapis Scilit Preprints.org Google Scholar Department of Biology, Center for Molecular Investigation of Neurological Disorders (CMIND), Pennsylvania State University, University Park, PA 16802, USAMemory is not a stable record of experience, but instead is an ongoing process that allows existing memories to be modified with new information through a reconsolidation-dependent updating process.Nicole C. Ferrara, 1 , 2 Janine L. Kwapis, 3 and Sydney Trask 4 , 5 , * Nicole C. Ferrara 1 Discipline of Physiology and Biophysics, Rosalind Franklin University, North Chicago, IL, United StatesThis work was supported by the National Institute on Drug Abuse (DA025922 to M.A.W. and DA041838 to A.J.L.), the National Institute of Mental Health (MH101491 to M.A.W. and G.L., and support to A.J.L.), the National Institute of Neurological Disorders and Stroke (NS085709 to G.L. and NS105217 to A.J.L.) and National Institute of General Medical ...Europe PMC is an archive of life sciences journal literature.Dina P. Matheos's 38 research works with 1,708 citations and 6,046 reads, including: Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's DiseaseAlzheimer's Disease affects 5.4 million Americans [1] and by 2030, approximately 13.8 million people 65 or older are projected to have the disease [2]. Even more individuals will experience normal age...Janine L. Kwapis ValeriaLallai MichaelS. Landy FionaE. N. LeBeau JaeK. Lee Christian H. Lemon JannaD. Lendner TylorR. Lewis Ya Dong Li Kyle P.Lillis Taosheng Liu DanielA.Llano HanbingLu HeikoJ. Luhmann Bryan W. Luikart Carl R.Lupica GyorgyLur KevinLuxem DingbangMa AngelaM. Mabb GuidoMaiello Joost X. Maier Elias Manjarrez MassimoMantegazza ...The Neuroscience section of the Current Protocols journal covers research methods involving molecular pathways, synaptic transmission, behavioral techniques & imaging.Thus, Per1 may independently function within the DH to regulate memory in addition to its known role in regulating the circadian system within the SCN. Per1 may therefore exert local diurnal control over memory consolidation within the DH. The circadian system influences many different biological processes, including memory performance. Janine L. Kwapis. Department of Neurobiology and Behavior, Ayala School of Biological Sciences, University of California, Irvine, CA, USA. UC Irvine Center for Addiction Neuroscience, Ayala School of Biological Sciences, University of California, Irvine, CA, USA. Search for more papers by this author.Janine L. Kwapis, PhD THE PAUL BERG EARLY CAREER PROFESSOR IN THE BIOLOGICAL SCIENCES; Assistant Professor of Biology. [email protected]. My research focuses on understanding the epigenetic and molecular basis of long-term memory. I'm particularly interested in understanding how these mechanisms are altered in the aging brain and how epigenetic ...Like reconsolidation, NMDA receptor activation is critical for memory extinction (Kwapis, Jarome, Lee, Gilmartin, & Helmstetter, 2014). Stimulation of β-adrenergic receptors by noradrenaline is known to potentiate fear memory extinction (Berlau & McGaugh, 2006; Mueller, Porter, & Quirk, 2008), while their inhibition by propranolol impairs it ...Bellfy, L.; Kwapis, J.L. Molecular Mechanisms of Reconsolidation-Dependent Memory Updating. Int. J. Mol. Sci. 2020 ... Janine Kwapis; Memory is not a stable record of experience, but instead is an ...Destiny S. Wright1, Kasuni K. Bodinayake1, Janine L. Kwapis1,* 1Department of Biology, Center for Molecular Investigation of Neurological Disorders (CMIND), Pennsylvania State University, University Park, PA, USA ... (Kwapis et al., 2019). This task is based on the object location memory (OLM) task (see Vogel-Ciernia & Wood, 2014) and therefore ...Previous work from our lab (Kwapis et al., 2015; Kwapis et al., 2014; Kwapis et al., 2011) has demonstrated that a 6-trial trace fear conditioning protocol with a variable intertrial interval (ITI) of 240 ±20s produces approximately the same level of freezing as 4 trials of delay fear conditioning with a shorter ITI of 110 ±20s. For both ...Finally, Bellfy and Kwapis review the evidence that the reconsolidation process may allow existing memories to update in response to new, relevant information . In their review, the authors outline the major behavioral paradigms used to study reconsolidation and describe the different molecular mechanisms across the brain that support this ...Quantitative real-time RT-PCR was performed to measure CREST expression following one-trial cocaine conditioning as previously described (López et al., 2016; White et al., 2016; Alaghband et al., 2017; Kwapis et al., 2017). Punches (0.5 mm) in the NAc were collected from 500 μm slices. All tissue was stored at −80°C until processing.Aug 20, 2018 · The work of Y.L., C.M., S.C., and P.B. was in part supported by NSF grant IIS- 1550705, DARPA grant D17AP00002, and NIH GM123558 to P.B. E.M. was supported by a long-term EMBO post-doctoral fellowship and an ARC Foundation award and work in the P.S.-C. lab was supported by grants from the National Institutes of Health, INSERM, and the Novo ... Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory. by Janine L Kwapis, Yasaman Alaghband, Enikö A Kramár, Alberto J López, Annie Vogel Ciernia, André O White, Guanhua Shu, Diane Rhee, Christina M Michael, Emilie Montellier, Yu Liu, Christophe N Magnan, Siwei Chen, Paolo Sassone …Propensity to relapse following long-periods of abstinence is a key feature of substance use disorder. Drugs of abuse, such as cocaine, cause long-term changes in the neural circuitry regulating reward, motivation, and memory processes through dysregulation of various molecular mechanisms, including epigenetic regulation of activity-dependent gene expression.Lauren Bellfy 1 , Janine L Kwapis 1 Affiliation 1 Department of Biology, Center for Molecular Investigation of Neurological Disorders (CMIND), Pennsylvania State University, University Park, PA 16802, USA. PMID: 32916796 PMCID: PMC7555418 DOI ...Janine l. kwapis
Author(s): Kwapis, Janine L; Alaghband, Yasaman; Kramár, Enikö A; López, Alberto J; Vogel Ciernia, Annie; White, André O; Shu, Guanhua; Rhee, Diane; ...Jun 1, 2023 · Additionally, the RSC has been demonstrated to play an important role in both the retrieval (Corcoran et al., 2011) and formation (Kwapis et al., 2015; Urban et al., 2021) of contextual fear memory. Both the anterior RSC (aRSC) and the posterior RSC (pRSC) have been implicated in spatial memory, although these subregions may each support ... Janine L Kwapis 1 , Fred J Helmstetter 2 Affiliations 1 Department of Psychology, University of Wisconsin-Milwaukee, 2441 E. Hartford Ave., Milwaukee, WI 53211, USA. Janine L. Kwapis a and Fred J. Helmstetter a Janine L. Kwapis a Department of Psychology, University of Wisconsin-Milwaukee, 2441 E. Hartford Ave., Milwaukee, WI 53211, USA Janine L. Kwapis, Ph.D., Department of Biology, Penn State University ... it is unknown whether these biological processes share a common mechanism that is altered with age. Dr. Kwapis will present evidence that epigenetic regulation of the circadian gene Period1 (Per1) in the dorsal hippocampus is critical for memory formation and contributes to age-related …Fear of movement-related pain leads to two types of avoidance behavior: excessive avoidance and pain-inhibited movement. Excessive avoidance is an absence of movement by fear, and pain-inhibited movements involve a change in motor behavior for the purpose of protecting the painful part. Here, we sought to clarify the acquisition process and adaptation of fear for each avoidance behavior ...30 Agu 2013 ... Jarome , Janine L. Kwapis , Wendy L. Ruenzel and Fred J. Helmstetter*. Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee ...Janine L. Kwapis, Timothy J. Jarome, Nicole C. Ferrara, Fred J. Helmstetter. Biology; Research output: Contribution to journal › Article › peer-review. 17 Scopus citations. Overview; Fingerprint; Abstract. Established memories undergo a period of vulnerability following retrieval, a process termed 'reconsolidation.' Recent work has shown ...Janine L. Kwapis, Y. Alaghband, +14 authors M. Wood. Biology, Psychology. Nature Communications. 2018; TLDR. It is shown that epigenetic regulation of clock gene Period1 in the hippocampus regulates memory and contributes to age-related memory decline, independent of circadian rhythms.Janine L. Kwapis, Timothy J. Jarome, and Fred J. Helmstetter ... (Kwapis et al. 2014), we predicted that the IL would be in-volved in the extinction of both types of memory.Timothy J. Jarome, Craig T. Werner, Janine L. Kwapis, Fred J. Helmstetter. Biology; Research output: Contribution to journal › Article › peer-review. 149 Citations (SciVal) Overview; Fingerprint; Abstract. Protein degradation through the ubiquitin-proteasome system [UPS] plays a critical role in some forms of synaptic plasticity. However ...Janine L. Kwapis, Timothy J. Jarome, Jonathan L. Lee, Marieke R. Gilmartin, Fred J. Helmstetter. Biology; Research output: Contribution to journal › Article › peer-review. 42 Scopus citations. Overview; Fingerprint; Abstract. Extinction learning underlies the treatment for a variety of anxiety disorders. Most of what is known about the ...Europe PMC is an archive of life sciences journal literature.How to say Janine L Kwapis in English? Pronunciation of Janine L Kwapis with and more for Janine L Kwapis.Deletion of Neuronal GLT-1 in Mice Reveals Its Role in Synaptic Glutamate Homeostasis and Mitochondrial FunctionYasaman Alaghband, Enikö Kramár, Janine L. Kwapis, Earnest S. Kim, Thekla J. Hemstedt, Alberto J. López, André O. White, Amni Al-Kachak, Osasumwen V. Aimiuwu, Kasuni K. Bodinayake, Nicole C. Oparaugo, Joseph Han, K. Matthew Lattal and Marcelo A. Wood. ... (DA025922) to K.M.L. and M.A.W., the National Institute of Mental …Janine L Kwapis 1 , Fred J Helmstetter 2 Affiliations 1 Department of Psychology, University of Wisconsin-Milwaukee, 2441 E. Hartford Ave., Milwaukee, WI 53211, USA.Europe PMC is an archive of life sciences journal literature.Chad W. Smies a, Janine L. Kwapis a, ∗ a Department of Biology, Pennsylvania State University, University Park, PA b Department ofNeurobiology and Behavior, University California, Irvine, CA a r t i c l e i n f o Article Aginghistory: both Received 17 OctoberAuthor links open overlay panel Yasaman Alaghband a b c, Janine L. Kwapis a b d, Alberto J. López a b c, André O. White a b c 1, Osasumwen V. Aimiuwu a b c 2, ... Kwapis et al. (2017) demonstrated that indeed the enzymatic activity of HDAC3 is required for amygdala-dependent forms of memory formation.Christopher W Butler 1 , Ashley A Keiser 1 , Janine L Kwapis 2 , Nicole C Berchtold 1 , Vanessa L Wall 1 , Marcelo A Wood 1 , Carl W Cotman 1 Affiliations 1 Department of Neurobiology and Behavior, University of California Irvine, Irvine, California 92617, USA.Collectively, this review will serve as a guide to assist neuroscientists in identifying and choosing the appropriate genetic tools available to study the complex relationship between the brain and behavior. Keywords: Transgenic mice, knockouts, Cre, DREADDs, CRISPR, brain, behavior. The development of transgenic mice dates back to the early ...Janine L. Kwapis, Ph.D. (she/her) principal investigator; The Paul Berg Early Career Professor in the Biological Sciences. Janine received her Ph.D. in Behavioral …The retrosplenial cortex is important for both the acquisition and retrieval of context fear, as blocking NMDA receptors within the RSC disrupts the retrieval of both recent and remote context fear memory (Corcoran et al., 2011) and blocking protein synthesis in the RSC or silencing the RSC during training impairs the acquisition of contextual ...Chad W Smies 1 , Kasuni K Bodinayake 1 , Janine L Kwapis 2 Affiliations 1 Department of Biology, Pennsylvania State University, University Park, PA 16802, USA. 2 Department of Biology, Pennsylvania State University, University Park, PA 16802, USA. Electronic address: [email protected]. PMID: 35697314 DOI: 10.1016/j.nlm.2022.107651 Abstract The …Janine L. Kwapis (University of California Center for the Neurobiology of Learning and Memory University of California) Yasaman Alaghband (University of California Center for the Neurobiology of Learning and Memory) Enikö A. Kramár (University of California Center for the Neurobiology of Learning and Memory) Alberto J. López (University of ...Curriculum Vitae Janine Kwapis 3 7. López AJ, Hemstedt TJ, Jia Y, Hwang PH, Campbell RR, Kwapis JL, White AO, Chitnis O, Scarfone VM, Matheos DP, Lynch G, Wood MA. (2019). Epigenetic regulation of immediate-early gene Nr4a2/Nurr1 in the medial 8.Janine L. Kwapis, Department of Biology, The Pennsylvania State University, 208 Mueller Laboratory, University Park, PA 16802, USA; e-mail: [email protected]. Metrics and citations MetricsWe have previously shown that trace fear extinction requires the RSC (Kwapis, Jarome, Lee, Gilmartin, & Helmstetter, 2014) and have hypothesized that trace …Aug 20, 2018 · The work of Y.L., C.M., S.C., and P.B. was in part supported by NSF grant IIS- 1550705, DARPA grant D17AP00002, and NIH GM123558 to P.B. E.M. was supported by a long-term EMBO post-doctoral fellowship and an ARC Foundation award and work in the P.S.-C. lab was supported by grants from the National Institutes of Health, INSERM, and the Novo ... Europe PMC is an archive of life sciences journal literature.Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory. by Janine L Kwapis, Yasaman Alaghband, Enikö A Kramár, Alberto J López, Annie Vogel Ciernia, André O White, Guanhua Shu, Diane Rhee, Christina M Michael, Emilie Montellier, Yu Liu, Christophe N Magnan, Siwei Chen, Paolo Sassone-Corsi, Pierre Baldi, Dina P Matheos, Marcelo A Wood.Brandon L. Roberts; Ilia N. Karatsoreos; Research Open Access 06 Jun 2023 Scientific Reports. ... Janine L. Kwapis; Research 01 Jun 2023 Neuropsychopharmacology. P: 1-9. All Research & Reviews.Janine L. Kwapis: Conceptualization, Methodology, Writing – original draft, Writing – review & editing, Supervision, Project administration, Funding acquisition. Declaration of Competing Interest. The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the …The best result we found for your search is Janine Lynn Kwapis age 30s in State College, PA in the Greentrees neighborhood. They have also lived in Shorewood, WI and Irvine, CA. Janine is related to Joseph Daniel Karbowski and Sonia B Kwapis as well as 3 additional people. Select this result to view Janine Lynn Kwapis's phone number, address, and more.Timothy J Jarome 1 , Janine L Kwapis, Craig T Werner, Ryan G Parsons, Georgette M Gafford, Fred J Helmstetter. Affiliation 1 Psychology Department, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53201, USA. PMID: 22723052 PMCID: PMC3381327 DOI: 10.1101/lm.024901.111 ...Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory. by Janine L Kwapis, Yasaman Alaghband, Enikö A Kramár, Alberto J López, Annie Vogel Ciernia, André O White, Guanhua Shu, Diane Rhee, Christina M Michael, Emilie Montellier, Yu Liu, Christophe N Magnan, Siwei Chen, Paolo Sassone …Janine L Kwapis1,2, Yasaman Alaghband1, Alberto J López1, André O White3, Rianne R Campbell1, Richard T Dang1, Diane Rhee1, Ashley V Tran1, Allison E Carl1, Dina P Matheos1 and Marcelo A Wood ...Author Note: Janine L. Kwapis, Timothy J. Jarome, Mary E. Lonergan, and Fred J. Helmstetter, Department of Psychology, University of Wisconsin-Milwaukee. We thank Ryan G. Parsons for technical assistance. This work was supported by National Institute of Mental Health Grants MH069558 (FJH) and MH060668 (FJH).Both the circadian clock and sex hormone signaling can strongly influence brain function, yet little is known about how these 2 powerful modulatory systems might interact during complex neural processes like memory consolidation. Individually, the molecular components and action of each of these sys …Check out Similar Professors in the Biological Sciences Department. 5.00 David Geiser. 5.00 James Howell. 5.00 Jan Van Riggelen. 0 Student Ratings. Janine Kwapis is a professor in the Biological Sciences department at Penn State University - see what their students are saying about them or leave a rating yourself.The major difference is that Parsons and Davis (2011a) infused a Indeed, preliminary research from the Sacktor laboratory has found volume of 0.5 l per hemisphere into the amygdala, as compared compensatory increases in PKC/ phosphorylation when PKM is J.L. Kwapis, F.J. Helmstetter / Brain Research Bulletin 105 (2014) 36–45 41Janine L. Kwapis, Timothy J. Jarome and Fred J. Helmstetter; Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, USA ... (NIMH) grants R01MH069558 to F.J.H. and NIMH grant F31MH090685 to J.L.K. We thank Marieke R. Gilmartin and Jonathan L. Lee for technical assistance. Previous Section Next Section ...Alaghband Y, Kwapis JL, López AJ, White AO, Aimiuwu OV, Al-Kachak A, Bodinayake KK, Oparaugo NC, Dang R, Astarabadi M, Matheos DP, Wood MA (2017) Distinct roles for the deacetylase domain of HDAC3 in the hippocampus and medial prefrontal cortex in the formation and extinction of memory.Author links open overlay panel Janine L. Kwapis, Marcelo A. Wood. Show more. Add to Mendeley. Share. ... DA031989) to M.A. Wood, and National Institute on Aging (NIA) T32 grant AG000096-31 to J.L.K. Glossary. Consolidation the process of converting temporary short-term memory (lasting only a few hours) ...Janine L. Kwapis, Timothy J. Jarome, Nicole C. Ferrara, Fred J. Helmstetter. Biology; Research output: Contribution to journal › Article › peer-review. 17 Scopus citations. Overview; Fingerprint; Abstract. Established memories undergo a period of vulnerability following retrieval, a process termed 'reconsolidation.' Recent work has shown ...Both the circadian clock and sex hormone signaling can strongly influence brain function, yet little is known about how these 2 powerful modulatory systems might interact during complex neural processes like memory consolidation.Janine L. Kwapis, 1 Yasaman Alaghband, 1 Alberto J. López, 1 Jeffrey M. Long, 2 Xiang Li, 1 Guanhua Shu, 1 Kasuni K. Bodinayake, 1 Dina P. Matheos, 1 Peter R. Rapp, 2 and ... AG051807, and AG050787 to M.A.W., the National Institute on Aging Grants F32 AG052303 and K99 AG056596 to J.L.K., and in part by the Intramural Research Program of the ...Histone deacetylase 3 (HDAC3) is the most highly expressed Class I HDAC in the brain, and this specific HDAC is a powerful negative regulator of learning and memory processes (Kwapis et al., 2017; Malvaez et al., 2013; McQuown et al., 2011; Rogge et al., 2013).Gilmartin, Marieke R.; Kwapis, Janine L.; and Helmstetter, Fred J., "NR2A- and NR2B-containing NMDA Receptors in the Prelimbic Medial Prefrontal Cortex Differentially Mediate Trace, Delay, and Contextual Fear Conditioning" (2013). Biomedical Sciences Faculty Research and Publications. 30.Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory. by Janine L Kwapis, Yasaman Alaghband, Enikö A Kramár, Alberto J López, Annie Vogel Ciernia, André O White, Guanhua Shu, Diane Rhee, Christina M Michael, Emilie Montellier, Yu Liu, Christophe N Magnan, Siwei Chen, Paolo Sassone-Corsi, Pierre Baldi, Dina P Matheos, Marcelo A Wood.Alzheimer's Disease affects 5.4 million Americans [1] and by 2030, approximately 13.8 million people 65 or older are projected to have the disease [2]. Even more individuals will experience normal age...Janine L Kwapis 1 , Timothy J Jarome, Marieke R Gilmartin, Fred J Helmstetter Affiliation 1 Department of Psychology, University of Wisconsin-Milwaukee, 2441 Hartford Ave., Milwaukee, WI 53211, USA.Timothy J. Jarome, Craig T. Werner, # Janine L. Kwapis, # and Fred J. Helmstetter * Efthimios M. C. Skoulakis, Editor. Author information Article ... Mouledous L, Frances B, et al. Protein degradation, as with protein synthesis, is required not only during long-term spatial memory consolidation but also reconsolidation. Eur J Neurosci. ...Histone acetylation is a fundamental epigenetic mechanism that is dynamically regulated during memory formation. Histone acetyltransferases (HATs) and histone deacetylases (HDACs) compete to modulate histone acetylation, allowing for rapid changes in acetylation in response to a learning event.Janine L. Kwapis, Timothy J. Jarome, Jonathan L. Lee, Fred J. Helmstetter. Biology; Research output: Contribution to journal › Article › peer-review. 64 Scopus citations. ... of two cues separated by an empty period of time. We have previously shown that trace fear extinction requires the RSC (Kwapis, Jarome, Lee, Gilmartin, & Helmstetter ...Alaghband, Yasaman ; Kramár, Enikö ; Kwapis, Janine L. et al. / CREST in the nucleus accumbens core regulates cocaine conditioned place preference, cocaine-seeking behavior, and synaptic plasticity.C.L. Bennett. Pages 44-57 View PDF. Article preview. select article Characterizing age- and sex-related differences in brain structure among middle-aged and older Hispanic/Latino adults in the study of Latinos- investigation of neurocognitive aging magnetic resonance imaging (SOL-INCA MRI) ... Alexandria R. McKenna, ... Janine L. Kwapis. Pages ...Janine L. Kwapis View These studies as a whole suggest that connectivity 498 between these regions, and not simply atrophy or brain volume, mediates circadian 499 phenotype and associated traits.Europe PMC is an archive of life sciences journal literature.It is established that CAMKII is active within the perirhinal region between ∼20 and 100 min following learning and then returns to baseline, which is essential for the consolidation of long‐term object recognition memory. The aim was to investigate the role of calcium‐calmodulin‐dependent protein kinase (CAMK)II in object recognition memory.Janine Kwapis Assistant Professor, Biology h-index 1482 Citations 24 h-index 2009 2023 Research activity per year Overview Fingerprint Network Grants & Projects (4) Research output (43) Similar Profiles (1) If you made any changes in Pure these will be visible here soon. Personal profileAU - Kwapis, Janine L. N1 - Funding Information: This work was supported by the National Institutes of Health (grants R00AG056596 and R21AG068444) awarded to J.L.K.; the Whitehall Foundation (grant 2020-05-06 to J.L.K.); and was conducted while Janine Kwapis was a Glenn Foundation for Medical Research and AFAR Grant for Junior Faculty …Fear of movement-related pain leads to two types of avoidance behavior: excessive avoidance and pain-inhibited movement. Excessive avoidance is an absence of movement by fear, and pain-inhibited movements involve a change in motor behavior for the purpose of protecting the painful part. Here, we sought to clarify the acquisition process …Following fear conditioning, behavior can be reduced by giving many CS-alone presentations in a process known as extinction or by presenting a few CS-alone presentations and interfering with subsequent memory reconsolidation.kwapis, janine lynn, phd * assistant professor department of biology pennsylvania state university university park, pa, 16802 li, zheng, phd principal investigator section on synapse development plasticity national institute of mental health national institutes of health bethesda, md, 20814 liu, siqiong june, phd * professor ...Janine L Kwapis 1 , Timothy J Jarome 1 , Nicole C Ferrara 1 , Fred J Helmstetter 1 Affiliation 1 Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, WI, USA. PMID: 28139682 PMCID: PMC5518901 DOI: 10.1038/npp.2017.23 Abstract Established memories undergo a period of vulnerability following retrieval, a process termed ...Injection of corticosterone (CORT) in the dorsal hippocampus (DH) can mimic post-traumatic stress disorder (PTSD)—related memory in mice: both maladaptive hypermnesia for a salient but irrelevant simple cue and amnesia for the traumatic context. However, accumulated evidence indicates a functional dissociation within the hippocampus such that contextual learning is primarily associated with ...The Neuroscience section of the Current Protocols journal covers research methods involving molecular pathways, synaptic transmission, behavioral techniques & imaging.. R34 roblox video